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2001) and inhibitors such as Dkk4 are expressed in the placodes and are secreted into the extracellular space, and can hence potentially participate in a reaction–diffusion system (Sick et al

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Studies show GSNO administration increases wound collagen content by 52.0% at day 5 and 47.5% at day 10 compared to controls, while maintaining physiological collagenolytic activity necessary for proper tissue remodeling

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